These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
If you're a Christian, this scene might hit even harder since after Shane explains to Adam exactly what happened, Adam says "Oh God help my daughter!"…and then she STILL dies. This leads into a series of scenes of the family grieving and then into a conversation between Adam and his wife where she tearfully talks about how "I'm in a black hole and I don't know where the way out is" (paraphrased). Many Christians can relate to unanswered prayers causing horrible pain.
Another way to look at "unanswered" prayers is that they simply don't get the answer you want, i.e. the answer you want is 'yes' and the answer you get is either 'no' or 'wait' (the prayer isn't answered on your preferred timetable.