These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Paranoia Fuel: LOTS. It's about a deadly virus and as realistic as it can be.
Watching this movie when you have a cold is ill-advised.
For fun, start coughing at random points during the movie. Works best in a crowded theater.
The film frequently lingers on shots of the various objects characters have touched to emphasize just how often our hands touch random things during daily life, and how many of those things others touch once they're done touching them.
Special Effects Failure: A minor one in a movie that really didn't have all that much in the way of special effects, but in several scenes it's obvious that Jude Law is wearing fake bad teeth, particularly in the close-ups during the on-air interview.
What an Idiot: Dr. Cheever's wife, who told her friend about the impending Chicago quarantine despite being specifically warned not to. The friend then posted it on Facebook, which gave Krumwiede ammo to use against Cheever and the CDC in general.