These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Base Breaker: Believe it or not even Reeve is not immune to this. While he was always well liked in the role of Superman his becoming an activist bordering on martyr for people suffering from spinal chord injuries only reinforced the association between him and Superman as he put himself out there as basically the poster child for spinal chord injury awareness. However, the occasionally obsessive association between him and the character of Superman by older fans (think people in the age ranges of Mark Waid and Geoff Johns) has also been known to alienate newer fans who did not grow up with his films and/or tend not to care for the Silver Age and BronzeAge sensibilities of his films, even if they harbor nothing personal against him, instead preferring the more modern interpretations from TV's Lois and Clark, the mid-90s DCAU series and even Smallville and Man of Steel in some cases. Naturally, this angers the older fans who view it as Fandom Heresy to not love the Reeve Superman films (the first two anyway).
Creator Worship/Dead Artists Are Better: To this day Reeve is the gold standard of any actor playing Superman on film, and sheer acting skill in a Super Hero role in general. His paralysis and later, his death only amplified the above in public and pop culture opinion.
Harsher in Hindsight: In the film Above Suspicion, he plays a paralyzed police officer. This was before his accident, but the end result is now the movie seems like a violation of his privacy.
The many feats of power, strength and heroism he performed throughout the Superman films - it's hard not to wince at them now in light of what happened to him later in life.
And then there's the bit in the fourth film where he pretends to wrench his back lifting weights.
This commercial for Nuveen Investments, which aired in 2000 during Super Bowl XXXIV.
Tear Jerker: Pretty much every appearance he made after his accident. Special mention goes to his Oscar speech and the standing ovation he received.