These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Older Than They Think: The idea of Red Skull's facial deformities being caused not by exposure to Dust of Death but a flawed version of the serum later used on the Captain, which was later adopted by Captain America: The First Avenger and some of the animated adaptations, actually originated in this film.