* HilariousInHindsight: "Hey, if you looked like Creator/RyanReynolds crossed with a shar-pei, you'd understand!" Although Avi Arad had said, before any production of a Wolverine movie, that if Deadpool was ever to be portrayed onscreen, he wanted Ryan to get the role. What makes this even better was apparently this panel was in the first issue of Deadpool that Ryan Reynolds ''ever read.''
* JerkassWoobie: Wade and Nate can plot and fight and do morally questionable things, but both of them have also had very hard lives that might just make the reader want to hug them.
* NightmareFuel:
** What happens to the kids whole first stole the virus in the first arc. They start melting in detail and it is ''creepy''.
** The Marauders in the ruins of Providence are very creepy, even fan-favorite X-Man Gambit. But Sabertooth killing Bashir takes the cake.