These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Nightmare Fuel: Yes, just yes. When anything nightmare fuel-y is happening, Straub switches to a more detailed style, allowing us to see in great detail how horrifying something is. Some fun examples:
Wadsworth has a dream where a patchwork skeleton is lying on a pile of his dictionary books.
Later on the same skeleton makes a surprise appearance between the panels of the comic as a reminder on why he shouldn't sleep.