- Best Known for the Fanservice: Not really, but one of the weirdest scenes may be the scene in which Higuide bangs Cute Monster Girl Illungorunuka a.k.a. The Octopus Princess
- Cargo Ship: Fuyu and Zouichi, admit it.
- Flat Character: Ion Green, yeah, she may be a more than 200 years old teenager which is the key to inmortality and being the antidote for the N5S Virus but she barely has anything to do with what was happening, and the fact that the manga has some Mind Screw here and there it's kinda easy to lost track of her, and hard to see her as a character rather than a Plot Device.
- Viewer Gender Confusion: Boots, one of the humans from the new world, it has chin length long hair and besides the fact that Nihei can only draw 2 or 3 faces for humans of both genders, is pretty similar to his sister.
- Writer Cop Out: While it has a great ending, and sheds some light on the future of the world of Biomega, just don't think too much on the last pages.