Final Apocalypse is the Distant Finale of The Tale of ALLTYNEX series.
While it's uncertain yet if Final Apocalypse has any connections to The Tale of ALLTYNEX, it's name seem to indicate as such.

Final Apocalypse will focus on ZODIAC Ophiuchus's destruction of the other ten ZODIACs
We never get to play out or even see cutscenes of Ophiuchus taking on the ten ZODIACs other than Virgo and Libra. Considering that the destruction of the ZODIACs led to apocalyptic levels of destruction to Earth's civlizations, this would be a good topic to explore for this upcoming game.