Sue's going to be the most successful of the threeY'know how Karma's a bitch, right? Well, it works the other way around when you're pretty much the biggest Chew Toy ever.
The whole series is actually a TV show created by...an adult Dewey. In order to cope with the insanity of his childhood, he decided to create a whole series based around it. Of course, he changed a few things like the names (he even wrote a daughter in!) as not to embarass his real family.
Brick is autistic.He does seem to manifest some of the characteristic signs of Asperger's syndrome, a high-functioning form of autism.
After Brad finally realizes he's gaySue will gladly become his Fag Hag slash BFF.
Dewey and his youngest brother had created The MiddleDewey and Jamie bonded their minds just as the series was over, entering a polar opposite of both family and friends. Dewey developed into Brick while Jamie matured into Axl. Reese's prank was a mark elaborated by Dewey and Jamie to choose who exists in this new universe. Sue is Lois as a child who's actually happy. Mike the perfected version of Hal. Frances is a younger Aida, a perpetually young woman chosen to happen because of Aida's attempt to rescue Dewey.
Zach Braff will appear as Mike's nemesis.He'll be an immature, obnoxious rival construction site owner. Why? Because both Doris Roberts and Ray Romano have appeared in Actor Allusion cameos for Patricia Heaton. It'd be funny if Neil Flynn got the same.
Brick deliberately plays up his Verbal Tic.Somehow, Brick's big brain gave him psychic/telepathic powers (90% of Your Brain illogical-ness aside) and he learned, from listening in on his parents' thoughts, that he was accidentally switched into the wrong family for a few weeks. Ever since then, he has lost his ability to trust anyone, and he therefore finds himself unwilling to form any social relationships with anyone, preferring the sheer escapism of books. In an effort to drive people away, he started repeating the last words he said, so people will want to leave him alone. note Just watch him with his new tic in "Bunny Therapy" note and tell me it doesn't look like he's doing it on purpose to dick around with everyone. It also has the added bonus of making his parents wonder what they did wrong with him...and then they remember, thus they are guilted forever. Brick, you are an evil genius.