There's more to this strip than meets the eye.The first thing that strikes me as odd is that the recipient of the award in Sandra's dream is MRS. North. You'd think that this is Sandra dreaming of herself when she gets older, but why would she be called MRS. North? This is because it's not just a dream to serve as the punchline to a joke. That was actually one of Sandra's memories of her mother before the latter passed away, hence why she wanted to make a name for herself in the field of math, and why the mere act of her not remembering a formula is depressing her so much (look at her face, it's not just disappointed, it's on the verge of tears.)
This is not Cloud using profanity.Instead, he's so frustrated that he can't form words at the moment, and is just grunting and screaming.
Sandra and Woo and Calvin and Hobbes exist in the same universe.Remember the "little raccoon" storyline which was one of the most tear-jerking moments in Calvin and Hobbes? Well, the raccoon didn't die. Instead, he crawled away after seeing what Calvin was capable of. Or maybe he was just afraid that Hobbes would have him for a snack. Calvin's dad, who couldn't quite admit this to him, made up the story of his death. (Note that we never actually see the raccoon, either alive or dead, in Watterson's artwork.) In the meantime, the raccoon was found by Mr. Farley, who caged him and generally treated him badly, until he grew old and wise enough to pick the lock of his cage, and escape into the city. Sandra found him (strip 1), took him home (strip 2), and that's where Sandra and Woo began. The trouble with this one is that it's not that wild.