Rayne is perfectly sane for the world in which LICD takes place.Everyone else just has a hyperactive Weirdness Censor. (The arc where he "hallucinated" a soldier telling him to nerf attack everyone was actually his sleep-deprived state allowing him to see the ghost of a guy who actually was crazy.) How else could you explain people noticing the talking llama?
It's been done before...But you have to admit, everything would make sense if he was either Jack Harkness and/or a Time Lord. Or, if you want to get technical, the child of a Time Lord *and* Jack Harkness. He will never know the truth, or why he has these powers... only that he has them.
Rayne's love life will go the way of Chobits.By which I mean that the series has been Cleaning Up Romantic Loose Ends now with Issa and Marcy dating someone else. At least in Issa's case, it was with a pre-established character. with Marcy, we never even met the guy, though. This will continue until everyone Rayne has actually had feelings for is taken, save for one. Or none, if that vision of the future comes to pass.
The girl from the most recent Beginnings is the one Rayne was crying about in his flashback sequence."Have to chase me" "Never going to stop". Huh.
The entire comic is subject to Rayne's Self-Serving Memory.Rayne is, like Scott Pilgrim, remembering the events of his own life in such a way that it makes him look like a perfect amazing sex god, and because he's the protagonist that's how the reader gets to see him. But in reality he's been rejected by most of the women he's been with (except for cases of pity sex), Marcy has him on an extremely short leash due to his horndog behavior and skipping work for the slightest reason, and his friends only hang around him out of a sense of obligation or because they're making sure that he doesn't get himself killed the next time he tries something stupid like making his own Iron Man suit. The delusions have been getting stronger as the series progresses, which is why the comic has seemed to bend even further to Rayne's liking (his friends stopped "whining", he can score even in ludicrous situations, etc).