- Executive Meddling: The reason this movie was directed and billed as a psychological thriller rather than a superhero origin story as Shyamalan originally intended. Arguably, this resulted in a more interesting and unique film.
- Hey, It's That Guy!: The doctor who sees Elijah's mother just after delivery is Kareem Said.
- The doctor who examines David after the train wreck is Doug Stamper, and David's wife is Claire Underwood.
- David's wife was once known as the most beautiful woman in the world: Princess Buttercup.
- The movie reunites Bruce Willis and Samuel L. Jackson, previously co-starring in Die Hard with a Vengeance.
- Playing Against Type: Samuel L. Jackson plays the near mirror-opposite of his previous roles: a weak, fragile, soft-spoken character. It's also fairly rare to see him play a villain as well.
- What Could Have Been: The Unbreakable Trilogy. However, not being such a success, it's just a stand alone story. M. Night has said he is waiting for the right script, then he will beg Disney to make the sequel.