Creator Backlash: John Kricfalusi does not like talking about this show, as it turned out far, far below his standards, and deviated too much from the goal of Spumco (i.e. everything was on-model, no custom poses or even the original pencil drawings were used) to the point where it felt like someone else's cartoon altogether.
Executive Meddling/Old Shame: John K claims the show was so watered down and far removed from what he originally planned it to be that he can hardly watch it. We can thank Canadian on-model standards for this.
Missing Episode: The episodes "The Infernal Wedding" and "Jimmy Gets Kidnapped" were left out of the Fox Kids broadcast of the series because it was just after 9/11 and the depiction of Citrocet as an evil foreign dictator who liked to blow up buildings was considered too controversial. (Oddly, they left in "Stinky Butt," which begins with Citrocet having already blown the Earth into multiple floating space chunks.) The episodes were added again during the [adult swim] airing. note It wasn't the only show on the FK lineup to be messed up as a result of the 9/11 attacks- several episodes of Transformers: Robots in Disguise were also pulled (and never aired in the US thanks to legal issues which have prevented reruns), and several episodes of Power Rangers Time Force were heavily edited.