Development Hell: This show tried to get off the ground for a few years, and when we finally had a premier date, it ended up getting pushed back about 3 times. The show's concept was overhauled at least once.
Name's the Same: Cartoon Network had an installment show that was named The Looney Tunes Show that ran from 2000 to 2004. Unlike this show, the first Looney Tunes Show was just a collection of classic Looney Tunes shorts from Cartoon Network's library (in a similar vein to CBS's "The Bugs Bunny Road Runner Show," ABC's "The Bugs Bunny and Tweety Show," The WB's "That's Warner Bros" [later renamed "The Bugs and Daffy Show"], FOX's "The Merrie Melodies Show," and Nickelodeon's "Looney Tunes on Nick").
The Other Darrin: Stan Freberg was going to reprise the role of Pete Puma, but was quickly replaced with John Kassir. The voice difference is highly noticeable compared to Freberg's Pete Puma voice.
Tina Russo Duck was voiced by Jennifer Esposito in Season 1, and now, in Season 2, is voiced by Annie Mumolo.
Lola's mother, Patricia, was voiced by Grey DeLisle in Season 1 and Wendi McLendon-Covey in Season 2.
Talking to Himself: Interesting that all of the characters in these examples are voiced by Jeff Bergman.
Tower Prep used to air on Tuesday nights at 8 PM, only for the ratings to drop and subsequent cancellation. The Looney Tunes Show premiered in the same timesloton the same nightand got spectacular ratings.