Fake American: Barry Morse (Gerard) was British. A good thing, too, since anytime a person on the street got too threatening to him for being mean to Kimble, he could switch to his native accent and say, "Blimey, Gov, I ain't who you think I am! Must be that bloke on the telly who looks like me."
Hey, It's That Guy!: Lots of familiar character actors, and future stars, appeared on this show.
It Will Never Catch On: Series creator Roy Huggins initially had great difficulty in selling the series to potential producers. Many of them felt that a series based on a wrongfully convicted man running from the law would be perceived as being too perverse, as well as a slap in the face to the American justice system.
You Look Familiar: Lots of actors will guest star in more than one episode in a different role. Perhaps the best example is Richard Anderson, who played Kimble's brother-in-law, Len Taft in the last 2 episodes. Anderson guest starred in 6 episodes total. The last 2 are the only ones where he played Len.
Neil Flynn's appearance even became a subplot in an episode of the show, in which it's implied that either the Janitor was in The Fugitive or that the Janitor is, in fact, Neil Flynn.
The Other Marty: Richard Jordan was originally cast as Dr. Charles Nichols, but he was extremely ill (he ended up passing away a few weeks after the film was released), thus being replaced with Jeroen Krabbe.
Spiritual Successor: David Twohy, one of the screenwriters for the film, went on to create The Chronicles of Riddick... a franchise solely about a Fugitive set in the distant future on absurdly inhospitable extrasolar planets.
Throw It In: Jones ad-libbed his famous "I don't care!" line (the scripted version was "It's not my problem") as well as many other comments his character makes.
Micheal Douglas, Kevin Costner, Andy Garcia, and Alec Baldwin were considered for the role of Richard Kimble. In fact, Baldwin was cast, but dropped out over a salary dispute. Meanwhile, Jon Voight and Gene Hackman were considered for the part of Samuel Gerard.
There were plans to make either Dr. Kathy Wahlund or Dr. Anne Eastman (Julianne Moore's character) a love interest for Kimble. This was nixed as (a) it would have been distateful for Kimble to take a new lover while trying to solve the murder of his wife (whom he was clearly still grieving for), and (b) such a story would have distracted from the "chase" aspects of the film.