A likely accidental example, considering both games came out in the same year, but Alexei, who is voiced by D.C. Douglas, mind controls the female lead into becoming his Dragon. He then forces her to fight the male lead, who must fight her to snap her out of it.Albert Wesker, also voiced by Douglas, did the exact same thing.
Cowboy BeBop at His Computer: For the longest time many thought that Estelle was voiced by Danielle Judovits after she hinted at voicing the role during the interview albeit noting that she didn't fully remember her involvement. It wasn't until recently when it was discovered that the "Claudia Lenz" alias belonged to Eden Riegel via her resume and not Danielle Judovits that Eden voiced the role instead. This even led many to falsely attribute Judovits to roles that Riegel in fact voiced such as in Fire Emblem Awakening.
The Danza: Coincidentally, Leblanc shares part of his surname with his English voice actor, JB Blanc.
Defictionalization: The "overdrive dolls", plush versions of each party member that can be equipped to Repede so that they ride on his back. Yuri's, Flynn's, and Rita's have been released as actual plushies.
The Other Darrin: The OVA Tales of Vesperia: The First Strike had its voicework outsourced to Funimation. As a result nearly every character had been recast (since Funi often uses a lot of Texas-based VAs, even though they have occasionally hired out-of state talent a few time.). The only exceptions are Troy Baker as Yuri Lowell and Sam Riegel as Flynn Scifo, who Funimation went out of their way to get back due to their popularity in the roles.
Even though it wasn't until recently when it was discovered she voiced the role, Estelle did the same for Eden Riegel who, following this game, went on to voice more roles in J-Games and even some anime. Though it wasn't until (once again) Persona 4 Golden when Eden got her name out there.