William Daniels, Terence Knox, Mark Harmon, David Birney, Stephen Furst, Alfre Woodard, Bruce Greenwood, France Nuyen, and Norman Lloyd all had regular roles as doctors.
Florence Halop had a recurring role as a grouchy old lady patient.
Patricia Wettig and Helen Hunt both played characters that Dr. Morrison was romantically involved with.
Ray Charles guest starred as a blind homeless blues man.