Also, at the end of her episode, Christina thinks she has discovered Spider-Man's secret identity. Everyone anxiously waits for her answer... only for her to reveal "Meng, the Drip-Den guy" as his true identity. She'd be closer to the truth than you'd think. Rino Romano voiced Meng, and previously voiced Spidey in Spider-Man Unlimited.
Executive Meddling: According to the producers, the network frowned on old people, hence why we barely saw J. Jonah Jameson and didn't see Aunt May (outside of a picture in one episode) or Robbie Robertson.
Talon was also originally supposed to be Black Cat until Eve was hired and MTV demanded she be changed to be closer to the singer.
According to Brian Michael Bendis, the network also frowned on unique and interesting stories. For example, Bendis pitched a story about how Peter Parker can't break away from college or various other commitments to go and fight the Rhino, which was an inversion on the standard superhero idea of the hero not being able to break from fighting the villain to honour his commitments. MTV snarled at the idea. Fortunately Bendis more-or-less said 'Screw you, I have other outlets' and the idea became Ultimate Spider-Man #28.
Fake American: Devon Sawa, who voices Flash Thompson, is Canadian.
Out of Order: Technically, many episodes, thanks to MTV and production order isn't much help, with only the order on the DVD set showing how they fit in continuity, but especially "Head Over Heels" and "The Party", "Head Over Heels" aired after the former and featured a pre-Electro Max Dillon, but "The Party" featured his transformation into Electro.
Screwed by the Network: It was a cartoon on MTV. It was doomed from the start. They burned through the episodes by airing a good chunk of the series with two episodes debuting on the same night for weeks.
Talon was originally going to be Black Cat, but was changed as soon as her voice actress, Eve, was cast.
Brian Michael Bendis spoke about how constraining it was to work on the series. Originally it was going to be something like Ultimate Spider-Man, but with college aged Peter Parker. However, Sony (or MTV or whoever) decided that it would be a movie tie-in instead.