Life Imitates Art: There have been a lot of coincidences between Shortland Street storylines and real life, that it has become known as the "Shortland Street Curse".
In 2003, Shortland Street Hospital had its back-up generator fail during a power outage - less than two weeks later, the same thing happened at Auckland's Starship Children's Hospital.
The Other Darrin: Justine Jones was recast with Lucy Wigmore in the role, who replaced Laurie Foell who had played Justine for the character's first two years on the soap.
Chris Warner's son Harry Warner has been played by four different actors since his birth: Joshua Thompson (2002), Callum Campbell Ross (2002-2006), Henry Williams (2006-2009), and Reid Walker (2009 onwards)
Daniel Potts was played for his first 3 years by Jarred Blakiston. When the character returned as a full member of the cast in 2009, he was turned into a "heartthrob" and so was recast with Ido Drent in the role instead.