- Actor Allusion: The song "These Arms of Mine" by Otis Redding is playing during the love scene. It was also the song playing in Dirty Dancing during the love scene between Patrick Swayze and Jennifer Grey.
- The original tagline referenced Swayze's role in that film: "The dancing's over. Now it gets dirty".
- Deleted Scene: Originally Keith David had a lot more scenes between he and Patrick Swayze, but most were deleted when it was determined that the final print ran too long, almost 2-1/2 hours. Some other deleted scenes include Dalton making the other bouncers wear ballet outfits and dance as part of their training. There is also a still picture showing Dalton fighting with Ketchum (the guy with the knife-boot) inside the Double Deuce in a different fight than the one in the film, and the theatrical trailer shows quite a few deleted and extended scenes.
- Missing Trailer Scene: The theatrical trailer shows some deleted scenes; Dalton grabbing some guy for mouth and telling him "Don't be rude!", Wade sitting on couch drinking a beer and saying "So says the fighting philosopher", Carrie Ann sitting in car with Dalton asking him "What's the matter, Dalton? Don't you like women?" and Dalton says "Best i ever had was wonderful", Dalton saying "I'm not afraid of him" in the scene where he talks with Doc before Emmet's house explodes, Wesley in bar after Red's shop has exploded and before fight scene telling Dalton, Red and others; "I guess you'll be having that fire sale now, huh Red?"
- The Other Marty: Kelly Lynch replaced Annette Bening.
- Ripped from the Headlines / Very Loosely Based on a True Story: The film was inspired by a real story where a local bad guy was killed in plain view. Nobody saw anything then either.
- Troll: Kelly Lynch revealed in an interview that every time Bill Murray or his brothers come across Road House on TV, they call up her husband right when the sex scene happens and proceed to troll him about Kelly Lynch taking it from Patrick Swayze. Every time.
- Vindicated by Cable: When it was first released, it got slammed hard by critics, who saw it as a Follow Up Failure for Patrick Swayze after the success of Dirty Dancing. But in The '90s, the number of cable channels exploded, all of which needed 24-hour programming. So the rights to lots of cheesy action movies were scooped up, and those movies put into heavy rotation. In particular, Turner (who owned TBS, the so-called "superstation") bought up the entire MGM film library, which just happened to include Road House. And it wasn't long before TBS discovered the movie was drawing phenomenal ratings; Perhaps Road House is the very reason TBS is a "superstation".
- Patrick Swayze (Dalton) and Ben Gazzara (Wesley) both died from pancreatic cancer. Swayze in 2009, and Gazzara in 2012.