Easter Egg: A few. One example is in the early Raccoon City stages, particularly in City Hall. Look at some of the paintings on the wall. Hey, isn't that Veronica Ashford? Yep, the Ashford family portraits can be found in the city. You can even encounter Alfred Ashford's in one of the rooms.
Word of Gay: According to the writers, Dee-Ay, the leader of the Spec Ops unit, is gay. His codename is a reference to "Don't Ask, Don't Tell".