Development Gag: In "The Medusa Bug" Phong explains that extended period being Taken for Granite by the Medusa Bug will eventually decompile low energy programs and up to high energy programs, showing an evolutionary chart of sorts displaying the hierarchy (street lamps - binomes - sprites). On the chart is a step between humanoid sprites and binomes of more blocky-looking humanoid form, which was the intended appearance of the main characters before they had the graphical power at what the show was eventually produced at.
Development Hell: The revival movie was announced on June 1st, 2008. As of April 2013, all that's come of that has been a teaser trailer and a single concept image, both released in 2009.
Executive Meddling: Many aspects of the show had to be changed due to censorship issues from the Broadcast Standards and Practices department at ABC. The creators understood at least some of the changes, even if they did not agree with themnote Bob not being allowed to jump through sheet glass made sense somewhat as it is possible to imagine a child imitating that and getting severely injured from it. However, some of the requirements were downright ridiculous. When celebrating Enzo's birthday, Dot (his sister) was not allowed to kiss him on the cheek since it was thought to be too incestuous. Ian Pearson, one of the creators, stated that he found the reasoning behind that decision "...one of the sickest things I've heard."
The show frequently lampshaded and lampooned the ABC censors and their decisions, with explicit references to the BS&P. There was even a song about it, set to the tune of YMCA by The Village People with lyrics that represented the writers' rants about Executive Meddling.
Also lampshaded in the note above. Instead of trying to figure out how to get Bob through the sheet glass, they teleport him through it by having Bob say "Glitch, BS&P."
Name's the Same: Dot Matrix isn't the same Dot Matrix from Spaceballs, though they are both named after the dot matrix printers of old.
Bob's voice actor changes midway through the series, then Bob's original voice actor came back as the "other" Bob in Season 4, and is promptly lampshaded by Dot by saying the "other" Bob "even sounds right." Original Bob even gets his original voice back after his original appearance is restored by Glitch.
Phillip Hayes voiced Hack in Season 1 and for most of Season 2. Scott McNeil took over from there and for the rest of the series.