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* ActorAllusion:
** In a deleted scene, Frank gets a shave at a perfume shop. Creator/HenryFonda sits in the same position he did in ''Film/MyDarlingClementine''. At the end of the film, he wears a similar outfit to the one he wore in ''Film/{{Warlock}}''. The latter film also contains a sequence in which Fonda's character kicks a crippled man off his crutches, as Frank does to Mr. Morton.
** This is the second western where Creator/CharlesBronson plays a harmonica, the first being ''Film/VeraCruz''. He also whittled a piece of wood in ''Film/TheMagnificentSeven''.
** Claudia Cardinale primping herself in front of a dirty mirror, recalling her appearance in Visconti's ''Film/TheLeopard''.
* DeletedRole: Lionel Stander's entire scene as the bartender was cut from international prints, but he remained on the credits.
* DeletedScene: In addition to the one above, a scene cut from the film has Harmonica being beaten up by the Sheriff. This explains why he has scars on his face.
* EnforcedMethodActing: The crew smeared jam onto Jack Elam's face so he'd intentionally attract flies. However, only one fly landed on his face so [[ThrowItIn they just went with it]].
* ExecutiveMeddling: Paramount left Creator/SergioLeone alone during the actual production, but they cut over 20 minutes of the film for international distribution, including the entire tavern sequence and [[spoiler:Cheyenne's death]]. This accounted in large parts for the film's cool reception upon release. Nor would ''West'' be Leone's [[Film/OnceUponATimeInAmerica last brush with studio editors, either]].
* FakeAmerican: Jill is played by Claudia Cardinale and Morton by Gabriele Ferzetti (both Italian).
* FatalMethodActing: Al Mulock, a Canadian actor playing one of the gunmen in the opening scene, committed suicide by jumping out a window (in costumes) between takes.
* PlayingAgainstType: Creator/HenryFonda plays the villain in this one, and a very vile one. Fonda had intended to radically change his usual appearance for the film, growing a mustache and beard and wearing brown contact lenses. Leone talked him out of it, as the shock of seeing good old Henry Fonda as a villain was exactly what he wanted. Ben Mankiewicz remarked on TCM that casting him as the villain hurt the box office, because viewers, especially Americans, thought he was too creepy.
* OrphanedReference: Harmonica has scars on his face at one point. This is from a deleted scene where he was beaten up by the sheriff.
* PromotedFanboy: Creator/SergioLeone considered Creator/HenryFonda his favorite actor since childhood, and had asked him to appear in all of his previous works (supposedly, Fonda's agent wouldn't even show him the scripts, [[ItWillNeverCatchOn thinking them beneath his client]]).
* RealLifeRelative: Woody Strode's wife plays the Indian woman who flees from the train station in the opening sequence.
* WhatCouldHaveBeen:
** Leone wanted Creator/ClintEastwood, Creator/LeeVanCleef and Creator/EliWallach- AKA Film/TheGoodTheBadAndTheUgly - to play the three gunmen in the opening scene, but Eastwood declined. Eastwood also turned down the role of Harmonica, as he was no longer interested in working with Leone.
** Creator/JamesCoburn was offered the role of Harmonica, but wanted too much money. Creator/WarrenBeatty, Creator/JeanPaulBelmondo and Creator/TerenceStamp were also considered.
** Carlo Ponti wanted to produce the film with his wife Creator/SophiaLoren playing Jill.
** Creator/EliWallach was meant to play Cheyenne, but Leone felt that he was too recognisable after ''Film/TheGoodTheBadAndTheUgly''. Again, he would have been a Mexican bandit, but this was changed when Jason Robards was cast. That's why Cheyenne, despite his American accent, speaks like English isn't his first language.
** Creator/KirkDouglas, an admirer of Leone, lobbied for the role of Cheyenne.
** Leone asked Robert Ryan to play the Sheriff of Flagstone. Ryan declined, preferring to film ''Film/TheWildBunch'' instead.

* Eli Wallach, who had starred in ''Film/TheGoodTheBadAndTheUgly'' a couple of years prior, had played a part in persuading Henry Fonda to take up the chance to work with Leone on ''Film/OnceUponATimeInTheWest''.
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