* ActorAllusion: In the anime, Shinonome Institute's resident talking cat Sakamoto is played by Creator/MinoruShiraishi, who, among other things (including [[Manga/HaruhiChan another]] FormallyNamedPet), played himself as the host of ''Manga/LuckyStar'''s "Lucky Channel" segment. In that show, his co-host Akira (played by HiromiKonno) sends him off on a suicide mission and replaces him with Creator/DaisukeOno. In this show, guess who plays the crow that the Professor (played by Hiromi Konno) decides would be better to have the talking scarf than Sakamoto?
** Another one in the same scene -- the fact that Ono plays a crow alludes to his role in ''VisualNovel/{{AIR}}''.
* FanNickname: "[[SmallGirlBigGun Gun]][[{{Tsundere}} dere]]" for Misato.
* HeyItsThatVoice:
** Sakamoto the cat is voiced by Creator/MinoruShiraishi!
** The principal is voiced by Cho, who also provides the voice for the principal in another well-known {{schoolgirl series}}: ''Manga/HidamariSketch''. He also voices Brook from ''Manga/OnePiece'', who shares a tendency toward {{Incredibly Lame Pun}}s.
** [[Creator/MaiAizawa Mio's voice]] is [[Anime/{{Munto}} Yumemi]], [[Manga/FutureDiary Minene Uryu]] [[Manga/LuckyStar Ayano Minegishi]] and [[VideoGame/BravelyDefault Edea Lee]].
** [[HiromiKonno The Professor]] is [[VideoGame/{{Amagami}} Sae]] and [[Manga/LuckyStar Akira Kogami]].
** The opening song is called [[http://www.youtube.com/watch?v=osWXbe7MbGE Hyadain's Kakakata Kataomoi-C]]. As in, [[http://www.youtube.com/user/hyadain2525 the very same Hyadain]] famous for video game remixes like [[http://www.youtube.com/watch?v=p3oi0ZacgoI The World Warrior]] and [[http://www.youtube.com/watch?v=m5hQpND9Xao Super Mario World Western Show]]; the OP is his professional debut single. And yes, true to his previous works, [[CrossDressingVoices he does sing the female vocals]], but the video has a female stand-in for those parts.
** He also made the second opening [[http://www.youtube.com/watch?v=1Xxnp0Q1GYQ Joujou Yuujou]].
** Sasahara is [[LightNovel/ACertainMagicalIndex Aogami Pierce]].
** The "Helvetica Standard" jingle is sung by the English Music/{{Vocaloid}}, Sweet Ann.
** Creator/DaisukeOno voices a crow in Episode 17.
** Minion #8 is voiced by HochuOtsuka in Episode 6 and 18.
** Manabu Takasaki is Creator/TetsuInada who also voiced [[Manga/{{Bleach}} Sajin Komamura]], and [[Series/TokusouSentaiDekaranger Doggie Kruger]]. It can come as a surprise, too, because Inada hasn't really done a purely comedy anime-[[http://uk.youtube.com/watch?v=pYsz3ytMQ3Y (Trombe!)]]
** The Narrator ('the Shinonome Laboratory had yet another peaceful day', 'Oh! Gentleman!') is Creator/BanjoGinga.
** The Negotiator is Creator/AkioOhtsuka.
** [[LightNovel/FateZero Kirei, Rider and Tokiomi]] all appear during the airship segment of Episode 21.
* NoExportForYou: Bandai was originally going to release this show in the US, but has since cancelled it due to financial troubles. Crunchyroll used to host it for streaming, but the streaming rights expired too, so the only way to enjoy the series now for English-speaking Japanese non-speakers is through fansubs.
* RelationshipVoiceActor: [[Creator/MaiAizawa Mio]] and [[HiromiKonno the Professor]]'s voices have shown up together before as [[Anime/{{Munto}} Yumemi and Suzume]], [[Manga/LuckyStar Ayano and Akira]], and [[Anime/KiddyGirlAnd Alisa and Letuchaia]].
** Yuuko and Mai were Kurimu and Minatsu in ''LightNovel/SeitokaiNoIchizon''.
** Professor and [[Creator/MinoruShiraishi Sakamoto]] were the hosts of [[Anime/LuckyStar Lucky Channel]]. And [[Creator/DaisukeOno the crow]] tried to usurp Sakamoto's place there, too.
** A creepier example, many characters are also voiced by ''Manga/FutureDiary'' {{seiyuu}}s. [[Creator/MaiAizawa Mio is Minene Uryuu aka Ninth]], [[Creator/MisuzuTogashi Mai is Yukiteru Amano aka First]], [[HiromiKonno the Professor is Kamado Ueshita aka Eighth]], [[Creator/MinoruShiraishi Sakamoto is Ouji Kosaka]], [[Creator/TetsuInada Takasaki-sensei is Ryuuji Kurosaki]], and [[Creator/TakayaHashi Dolph is John Balks aka Eleventh]]. And the [[Creator/NorioWakamoto Wooden Cubes are Deus Ex Machina]].
* StuntCasting: The anime adaptation has formed a habit of having a well-known voice actor speak as one of the important objects that appears in the episode.
** Episode 1: [[http://www.animenewsnetwork.com/encyclopedia/people.php?id=3557 Reiko Katsura]] as Nano's little toe.
** Episode 2: [[http://www.animenewsnetwork.com/encyclopedia/people.php?id=2076 Masako Ikeda]] as the cake in Nano's head.
** Episode 3: [[http://www.animenewsnetwork.com/encyclopedia/people.php?id=3095 Hiroshi Masuoka]] as a Voodoo doll.
** Episode 4: NorikoOhara as an apartment building.
** Episode 5: Creator/RikiyaKoyama as an onomatopoeia.
** Episode 6: Creator/FumihikoTachiki as the 10-Yen soccer coins.
** Episode 7: Creator/NorioWakamoto as the wooden cubes (and also a soldier at the start of the episode).
** Episode 8: Creator/TomokazuSeki as a double-yolked egg.
** Episode 9: Creator/AyaHirano as the ''shogi'' King tile and the angel from ''Helvetica Standard''.
** Episode 10: Creator/MasakoNozawa as an origami frilled-neck lizard.
** Episode 11: [[http://www.animenewsnetwork.com/encyclopedia/people.php?id=2176 Fuyumi Shiraishi]] as balls made of mud and steel.
** Episode 12: Creator/SatomiKoorogi as a bottle of cider.
** Episode 13: Creator/MegumiOgata as a string of international flags.
** Episode 14: Creator/ShigeruChiba as a soccer ball.
** Episode 15: Creator/YoshikoSakakibara as a can of oil.
** Episode 16: [[http://www.animenewsnetwork.com/encyclopedia/people.php?id=1592 TARAKO]] as a plus-screw.
** Episode 17: Creator/KazuyaNakai as the Three of Spades.
** Episode 18: RikakoAikawa as a sweet grande white chocolate mocha frappuchino, ordered with a short single-shot caramel sauce, hazelnut syrup, chocolate chip, extra whip espresso.
** Episode 19: Creator/YujiMitsuya as Yuuko's clay bust of herself.
** Episode 20: Creator/MamiKoyama as manga manuscript paper.
** Episode 21: Creator/SumiShimamoto as a "Lovers' Umbrella".
** Episode 22: [[http://www.animenewsnetwork.com/encyclopedia/people.php?id=2172 Shibata Hidekatsu]] as melon bread.
** Episode 23: Creator/YuiHorie as the high school graduation photo of Sakurai-sensei.
** Episode 24: [[http://www.animenewsnetwork.com/encyclopedia/people.php?id=1529 Ichirou Nagai]] as a vending machine.
** Episode 25: KeikoYokozawa as Nano's wind-up key.
* TheWikiRule: See [[http://nichijou.wikia.com/wiki/Nichijou_Wiki here]].