* AcclaimedFlop: The anime wasn't very financially successful in Japan, and it's Creator/KyotoAnimation's lowest-selling anime to date. However, it was well-received by critics and it garnered a sizeable fanbase in North America and Europe.
* ActorAllusion: In the anime, Shinonome Institute's resident talking cat Sakamoto is played by Creator/MinoruShiraishi, who, among other things (including [[Manga/HaruhiChan another]] FormallyNamedPet), played himself as the host of ''Manga/LuckyStar'''s "Lucky Channel" segment. In that show, his co-host Akira (played by Creator/HiromiKonno) sends him off on a suicide mission and replaces him with Creator/DaisukeOno. In this show, guess who plays the crow that the Professor (played by Hiromi Konno) decides would be better to have the talking scarf than Sakamoto?
** Another one in the same scene -- the fact that Ono plays a crow alludes to his role in ''VisualNovel/{{AIR}}''.
* FanNickname: "[[SmallGirlBigGun Gun]][[{{Tsundere}} dere]]" for Misato.
** Also "Eh-chan" for Haruna Annaka.
* NoExportForYou: Bandai was originally going to release this show in the US, but has since cancelled it due to financial troubles. Crunchyroll used to host it for streaming, but the streaming rights expired too. The only way to enjoy the series legally for English-speaking Japanese non-speakers is buying from Madman Entertainment, an Australian company which licensed the series for english for Australia and New Zealand on streaming and DVD. Whether an actual English dub will ever be made is unknown, though with the amount of Japanese puns that wouldn't translate well, it seems unlikely.
* RelationshipVoiceActor: [[Creator/MaiAizawa Mio]] and [[Creator/HiromiKonno the Professor]]'s voices have shown up together before as [[Anime/{{Munto}} Yumemi and Suzume]], [[Manga/LuckyStar Ayano and Akira]], and [[Anime/KiddyGirlAnd Alisa and Letuchaia]].
** Yuuko and Mai were Kurimu and Minatsu in ''LightNovel/SeitokaiNoIchizon''.
** Professor and [[Creator/MinoruShiraishi Sakamoto]] were the hosts of [[Anime/LuckyStar Lucky Channel]]. And [[Creator/DaisukeOno the crow]] tried to usurp Sakamoto's place there, too.
** A creepier example, many characters are also voiced by ''Manga/FutureDiary'' {{seiyuu}}s. [[Creator/MaiAizawa Mio is Minene Uryuu aka Ninth]], [[Creator/MisuzuTogashi Mai is Yukiteru Amano aka First]], [[Creator/HiromiKonno the Professor is Kamado Ueshita aka Eighth]], [[Creator/MinoruShiraishi Sakamoto is Ouji Kosaka]], [[Creator/TetsuInada Takasaki-sensei is Ryuuji Kurosaki]], and [[Creator/TakayaHashi Dolph is John Balks aka Eleventh]]. And the [[Creator/NorioWakamoto Wooden Cubes are Deus Ex Machina]].
* StuntCasting: The anime adaptation has formed a habit of having a well-known voice actor speak as one of the important objects that appears in the episode.
** Episode 1: [[http://www.animenewsnetwork.com/encyclopedia/people.php?id=3557 Reiko Katsura]] as Nano's little toe.
** Episode 2: [[http://www.animenewsnetwork.com/encyclopedia/people.php?id=2076 Masako Ikeda]] as the cake in Nano's head.
** Episode 3: [[http://www.animenewsnetwork.com/encyclopedia/people.php?id=3095 Hiroshi Masuoka]] as a Voodoo doll.
** Episode 4: Creator/NorikoOhara as an apartment building.
** Episode 5: Creator/RikiyaKoyama as an onomatopoeia.
** Episode 6: Creator/FumihikoTachiki as the 10-Yen soccer coins.
** Episode 7: Creator/NorioWakamoto as the wooden cubes (and also a soldier at the start of the episode).
** Episode 8: Creator/TomokazuSeki as a double-yolked egg.
** Episode 9: Creator/AyaHirano as the ''shogi'' King tile and the angel from ''Helvetica Standard''.
** Episode 10: Creator/MasakoNozawa as an origami frilled-neck lizard.
** Episode 11: [[http://www.animenewsnetwork.com/encyclopedia/people.php?id=2176 Fuyumi Shiraishi]] as balls made of mud and steel.
** Episode 12: Creator/SatomiKoorogi as a bottle of cider.
** Episode 13: Creator/MegumiOgata as a string of international flags.
** Episode 14: Creator/ShigeruChiba as a soccer ball.
** Episode 15: Creator/YoshikoSakakibara as a can of oil.
** Episode 16: [[http://www.animenewsnetwork.com/encyclopedia/people.php?id=1592 TARAKO]] as a plus-screw.
** Episode 17: Creator/KazuyaNakai as the Three of Spades.
** Episode 18: Creator/RikakoAikawa as a sweet grande white chocolate mocha frappuchino, ordered with a short single-shot caramel sauce, hazelnut syrup, chocolate chip, extra whip espresso.
** Episode 19: Creator/YujiMitsuya as Yuuko's clay bust of herself.
** Episode 20: Creator/MamiKoyama as manga manuscript paper.
** Episode 21: Creator/SumiShimamoto as a "Lovers' Umbrella".
** Episode 22: [[http://www.animenewsnetwork.com/encyclopedia/people.php?id=2172 Shibata Hidekatsu]] as melon bread.
** Episode 23: Creator/YuiHorie as the high school graduation photo of Sakurai-sensei.
** Episode 24: Creator/IchiroNagai as a vending machine.
** Episode 25: Creator/KeikoYokozawa as Nano's wind-up key.
* TheWikiRule: See [[http://nichijou.wikia.com/wiki/Nichijou_Wiki here]].