Approval of God: Series creator Maureen Jennings is a big fan of the series, even though it's different in many ways from her original novels. She has served as a creative consultant throughout the show's run and has even directly co-written a few scripts. She has also declared that Yannick Bisson looks exactly the way she imagined Murdoch in the novels...except for the moustache she always gave him.
California Doubling: Set in Toronto but filmed in Cambridge and other smaller downtowns across Ontario as none of the streets of modern Toronto looks like 1890s Toronto. Averted in "Ghosts of Queen's Park", which did indeed film inside the Ontario Legislative Building at Queen's Park.
The Danza: Thomas Craig as Inspector Thomas Brackenreid.
Directed by Cast Member: Yannick Bisson has directed "Buffalo Shuffle," "Murdoch at the Opera," "Murdoch and the Cloud of Doom," and "Murdoch of the Living Dead."
Fake Nationality: Canadian Dr. Ogden is played by Australian actress Helene Joy.
Mary Walsh and Gavin Crawford, playing a grieving mother of a murdered daughter and a possibly insane puppeteer, respectively. Both are best known as anchors on the comedy news show This Hour Has 22 Minutes.
Michael Seater's chilling performance as the psychopath James Gillies is a far cry from his previous teen sitcom roles.
Short Run in Peru: Despite being a Canadian-produced series, new episodes air much earlier in the UK. Averted with series 6 — it began airing in Canada a month before the UK.