- Dummied Out: The North American release of 2 has a few particular monster species that had some of their techs locked out due to censoring reasons and/or bad porting of the Japanese version, with the only way to unlock them is through the use of a GameShark. The Kato species, for an example, had its affinity for sake changed to olive oil and its particular attacks based on it were removed, making it impossible to unlock them while sending it on an Errantry.
- No Export for You:
- The original Monster Rancher never came out in PAL regions.
- The first DS game was never released outside Japan.
- Monster Farm Online, the MMORPG. Even if you go through the trouble of singing up for a Japanese account, you can't play it because it blocks all foreign IPs.
- Monster Farm POP 1, 2, and Monster Farm Travel were never released outside Japan.
- Sequel First: The original Monster Rancher never came out in PAL regions—instead, its sequel, Monster Rancher 2, came out first with the number dropped. This caused certain aspects of the anime and the spinoff games to become cases of Marth Debuted in "Smash Bros."—the Dino species were MR1 only.
- Similarly, the original DS game never came out in English. English-speaking markets got DS 2 instead, with the similarly-dropped number.
- Dueling Shows: To Digimon and Pokémon back in 1999.
- Keep Circulating the Tapes: For years the only first season was released on VHS, and all the DVDs are out of print. Eventually averted when Hulu began to stream the entire anime. Later, Discotek would rescue the series.
- Missing Episode: The episodes "Tiger's Battle with Destiny" and "The Battle with the Big Bad Four" only aired once, and were taken out of syndicated airings. Despite being important to the plot, they were never shown in syndication.
- Network to the Rescue: The syndicated BKN broadcasted the anime early weekday mornings, and only reran (repeatedly) the first season. Fox Kids not only ran the first season on it's Saturday morning line-up, but also broadcasted the second season. Unfortunately, they only ran the second season in full once.
- ABC Family (at the time, Fox Family) however did run the second season a few times. However, for some reason, they never aired "Tiger's Battle with Destiny" and "The Battle with the Big Bad Four".
- The Other Darrin:
- Genki Sakura's voice actor changed from Saffron Henderson to Andrew Francis. The reason for this is the former's wedding, which took place sometime in January or February 2001, conflicted with her voice acting commitments.
- Golem's voice actor changed midway through season 2 from Richard Newman to Doc Harris.
- Monol was voiced by David Kaye in the first season before being replaced by Brian Drummond in the next two seasons.
- On the Japanese side of things, Tsutomu Kashiwakura replaced Kaneto Shiozawa as Gali during season 3 after the latter passed away between appearances.
- Post-Script Season: The third season was produced after it was Un-Canceled. And after the shock of the second season's ending, the third season was... a jarring shift, to say the least.
- Retroactive Recognition: Hare's voice is the same one Samuel Vincent uses for Double D.
- Screwed by the Network: The first season was rerun into the ground, and the second season was only aired in full once, with two episodes swiftly being removed from rotation afterward: "Tiger's Battle with Destiny" and "Battle with the Big Bad Four": the final confrontations with Gray Wolf and Naga. The third season was dubbed but never aired in the US.
- Talking to Himself: Besides Genki Sakura, Saffron Henderson also voices Pixie. The said characters had a conversation in episode 10.
- Unintentional Period Piece: Genki is playing his game on a Playstation 1 expy. In the dub, Genki taunts a robot by claiming "I heard your mother was the Y2K Bug!".