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Tracey Ullman, star of several sketch comedy programs and voice of the Emily Winthrop character in The Simpsons episode "Bart's Dog Gets an F", plays the role of Lulu in the 1990s HBO series The Little Lulu Show for the first season. Also from the 90's show, Tubby is voiced by the same voice actor who played Binky from the PBS animated TV show Arthur.
Likewise, Annie was originally voiced by the boy who originally voiced D.W. on Arthur.
For the last two seasons of the 1990s series, Lulu was voiced by the same actress who dubbed the voice of YaYa from Wimzie's House.