There are fans who called Kyoko "Miss Sparkles" due to how she always had the sparkling effect when smiling.
Genre Shift: Katekyō Hitman Reborn!becomes an action series. This is not clear from the beginning. And the main character is still fighting with a pair of woolen mittens secreted by a shapeshifting chameleon long after the series stumbled into Serious Business territory. Magical pacifiers are also involved in the plot and are not played for laughs either. Not to mention that the Italian mafia apparently hires magical baby hitmen to go train their future boss... Or that it's a common staple for mafia bosses to be able to fly around shooting flames out of their hands and Tetratrillions of worlds. So yeah...
The Other Darrin: In the anime, Dino was voiced by Kenta Kamakari, but after Episode 34 he was replaced by KENN.
Playing Against Type: Kiuchi Hidenobu, whose more famous roles include the composed and usually taciturn Hei of Darker Than Black and the thoughtful, considerate hero of Dr. Tenma in Monster, plays Sasagawa Ryohei TO THE EXTREME!