The TV series:
- Acting for Two: Robert Culp as Kelly and the General in "The Warlord".
- Actor Allusion: In "Little Boy Lost" Scott talks about childhood friends including Weird Harold, imortalized both in Cosby's standup routines and later as a character on Fat Albert and the Cosby Kids.
- In "The Trouble with Temple", Scotty tries to fight mind control by blurting out "My name is Fat Albert and I walk like a duck!" when asked for his name.
- Cosby and Scotty also share the hometown of Philadelphia.
- California Doubling: Unlike just about every other spy series of the time, averted (although there was still some filming done in Hollywood, there was no "Somewhere In (Insert Foreign Country Here)" cheating on this show).
- Throw It In: Much of the banter between Cosby and Culp was ad-libbed.
- Written and Directed by Cast Member: Robert Culp wrote seven episodes and also directed one of his scripts ("Court of the Lion").
The picture books:
- Milestone Celebration: I Spy Mystery, which celebrates the series' 10th anniversary, and I Spy Spectacular, which celebrates the series' 20th anniversary.
- Recycled Script: Well, not so much "script", but the Challenger books all reuse pictures from the previous books with newer (and usually much more difficult) riddles.