* ActorAllusion: In the 1980s TV series ''Series/{{V}}'', one of the important characters is a battle-hardened Resistance leader fighting against the Visitors, a group of extraterrestrial lizard-people. In this movie, the [[BigBad main villain]] is a psychotic human warrior fighting ''with'' a group of lizard-men as their leader (see below). Both characters are named Tyler, and both roles are played by MichaelIronside.
* FollowTheLeader: ''Film/TheFifthElement'' borrows heavily from the Harry Canyon segment.
* SuspiciouslySimilarSong: Music/ElmerBernstein reworked some of his ''Heavy Metal'' score as "Dana's Theme" from ''Film/{{Ghostbusters}}''.
* WhatCouldHaveBeen: The plot was meant to be connected and more complex than an anthology, but due to the release date being bumped up and a rushed production, the animation had to be done by several animation houses, including [=CinéGroup=] and Atkinson Film-Arts. Some of the ideas were Hanover Fiste showing up in So Beautiful, So Dangerous, appearing on Zeke and Edsel's ship, saying "Sternn will go free!" and a sequence linking Sternn and B-17 called Neverwhereland, wherein the Loc-Nar lands on a planet and affecting its development.
** Kyle Gass had revealed that the director of ''WesternAnimation/KungFuPanda'' had approached Music/TenaciousD with an idea for a remake of Heavy Metal. The band was to appear in it as a duo of alien stoners, and they even composed the song [[XtremeKoolLetterz "Deth Starr"]] for the film. Unfortunately, though, the idea never came to pass for fear that [[AnimationAgeGhetto an R-rated cartoon would not sell well]], so the band ended up releasing the song years later on their album ''Rize of the Fenix''.

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