- Adaptation First: The 13-episode anime series is the only part of the Gokusen franchise that got exported stateside.
- Dawson Casting: Avoided in the live-action series. High school seniors 17-18 are played by actors aged 18-22.
- Hey, It's That Guy!: Wait, Yankumi is... Sadako?
- Hey, It's That Voice!: Miss Kumiko Yamaguchi will become Mami Tomoe, Satsuki Kiryuin, and Casca in the future.
- Portmanteau Series Nickname: Gokudo no Sensei - translates to Gangster Teacher