Most of the Quickies (including all the U.S. Acres quickiesnote except for the fake one in Moo Cow Mutt and all "Screaming with Binky" segments except for one note The one that was kept in syndication was the one where Wade fills in for Binky. were edited out of The Program Exchange's prints, as was the original theme song, replaced with the "We're Ready To Party" theme song used in seasons 3-6. The last three seasons weren't seen in reruns after the show ended its run either, as CBS declined to sell them the rights.
After CBS stopped showing the show on Saturday mornings, people never got to see (or rewatch) the last three seasons until they finally came out on DVD. Which is a shame because not only were the last three seasons the funniest, but they also show Roy and Wadebecoming closer friends in comparison to the earlier seasons. Something that people only familiar with the syndicated episodes didn't get to see...
The show was broadcast in Finland in a format that dropped the U.S. Acres segments but kept the opening titles. It was bizarre having characters in the titles that never appeared in the show. Considering what happend in their dub of the episode "Peace and Quiet" (where Binky sings off key) and that "Wanted: Wade" had a scene where Wade does a "song" which is a rap with him talking instead of singing as if it were Go Animate, it could have been a lot worse.
Also, it appears the Japanese version dropped the segments featuring US Acres on both of their dubs of the show! And how do we know this? On a Japanese blog, there aren't Japanese names for any US Acres episodes, and the US Acres bug quickie is replaced by "Screaming with Binky." They also only dubbed the first four seasons.
In Malaysia, the U.S. Acres segments had all scenes with Orson Pig edited to appease Muslim audiences (as pigs — whether used as food or not — are considered offensive to the Muslim religion and Malaysia has a sizeable population with people of that religion).
Executive Meddling: During the seventh and final season of the show, the series' traditional "We're Ready to Party" intro was replaced with a rap-like intro that everyone ranging from fans of the show to the creators hated—the rap intro was only used on the original CBS airings. It was not used in international airings and as a result does not appear on the series' DVD boxsets (which use the international version of the series).
CBS also wanted to cut the budgets of Garfield and all its other animated shows, the creators refused to give in and decided to end the show rather then letting it suffer from the cutbacks.
Fake Russian: Averted in "Swine Trek." In Orson's Star Trek-based dream where he's The Kirk of his barn-shaped starship, Booker, as Chekov's counterpart, is dressed like the stereotypical Russian Cossack, complete with beard. Frank Welker, Booker's VA, speaks in a believable Russian accent, with a commenter on the clip using Google Translate to put in the comments the Cyrillic Russian for Booker's line at 3:58. Booker speaks Russian again at 4:43, and Roy at both times must ask for translations. Leading to Lanolin as "Uhura" snarking "Flunked Russian at the Space Academy, didn't ya?"
Victoria Jackson (a ditzy, blond comedian known for doing headstands and body contortions while reciting poetry. She was in the movie UHF and was a cast member on Saturday Night Live during the 1980s) played Garfield's on-again-off-again love interest, Penelope Pussycat.
Eddie Lawrence played The Feline Philosopher
Imogene Coca played The Fairy Dogmother
Kevin Meaney played Aloysius Pig.
Will Ryan voiced McCraven the ghost.
Gary Owens voiced the announcer in a certain segment, he was even CALLED 'Gary'!
The original version of "Orson Goes On Vacation" is this as well, since it shows the full-size U.S. Acres logo at the beginning. The DVD replaced this with the Orson's Farm logo.
Two Screaming With Binky segments are missing from the DVDs and from international broadcasts (possibly for time): one about baseball, and another about a pizza parlor. No info can be found on the former, but the Platypus Comix page on the series has a summary on the latter.
The "rap" theme song used only in American airings of Season 7.
Recycled Script: The Quickies are mostly adaptations of the Sunday strips (at least one was based on a daily strip, and at least two have a direct Call Back to the preceding cartoon), but the main cartoons themselves derive from the strips, especially in the earlier episodes. For example, the episode "Caped Avenger" is an episode where Jon takes Pooky to wash him and pitches ideas for a new comic strip, but is otherwise based on two weeks of strips where Garfield, as the Caped Avenger, adopts Odie as Slurp, his sidekick (specifically, August 26-31, 1985 and September 2-7, 1985). To the cartoon's credit, it did add an additional costume gag that wasn't in the strips:
Garfield: Slurp, you really need a costume if you're gonna work with me. (Odie runs off, then comes back wearing a chicken suit) Garfield: You still haven't grasped the principle behind this.
It also had a subplot involving Jon trying to pitch comics to a visiting expert that wasn't in the original strips.
Season 7's "Clash of the Titans" repeated the plot from Season 2's "Attack of the Big Robots"
Screwed by the Network: As mentioned above, CBS wanted to cut the show's budget despite the fact that the show was still pulling in strong ratings. The creators, instead, decided to end the show rather than let it suffer from budget cuts.