One indication Spiro Agnew is out of touch with reality early on is when he seriously talks about restoring the Kuomintang to ruling mainland China. A decade later, partly as a result of Agnew's policies, mainland China has become a nightmarish dictatorship and then disintegrated, allowing the Kuomintang to, indeed, return from Taiwan to rule parts of it.
With the Timeline itself, the rise of an Islamic Caliphate in Syria, Islamist insurgency in Mali, a Latin American Pope with a very left-wing view on capitalism and a USA President openly willing to assassinate terrorists' relatives happened both in-universe and in real life.
Dead Fic: Sadly looking to end up like this. The last update came in July 2016 and the author hasn't been seen since August 2017.