The Red Stapler: The Detroit Zoo fountain snowglobe was eventually produced as an actual zoo souvenir after the film was released.
Star-Making Role: For Laika Animation themselves, whose success with the film lead to closing their CG Features division in favor of a stop motion division.
What Could Have Been: The movie was originally planned as a musical with 10 songs written by They Might Be Giants, but this idea was discarded in favor of a more conventional movie, although one of their songs (the Other Father's number) does remain in the film, and the band has said they will release the other songs written for the movie on other projects ("Careful What You Pack", for example, wound up on their 2007 album The Else).
The film at one point had plans to use CGI for the Other World segments, and Normal Claymation for the Real World segments.
There was a lot of discussion about the famous Other Spink and Other Forcible performance, specifically exactly how much they could get away with. Selick said he convinced the company to let it slide because Other Forcible was not only covering her naughty bits, but was also spoofing a socially acceptable, famous painting.
The movie's production took five years, at the rate of roughly three seconds a day.
It is the first stop-motion movie to be produced in 3D. As the side-by-side camera rig commonly used in live-action shoots cannot fit into the miniature sets, not to mention unable to create the desired results, the camera crew solved this by building a camera rig that slightly move the camera sideways after each take and take a second picture, resulting in the 3D effect seen in the movie.
Most of the non-stop-motion effects are either hand-drawn or shot in live action, with as few CG effects as possible.
The character Wybie Lovat was not in the original book, and was added following producer Bill Mechanic's suggestion. The decision is approved by Neil Gaiman.
Throw It In: The scene with Other Spink and Other Forcible was originally meant to have a song written by They Might Be Giants (as was a lot of the rest of the film, but that's another matter). After hearing the placeholder song the writers had come up with, John and John said it was good enough and there was no reason to replace it.