* CreatorCameo: Well, ''writer'' cameo, actually. Co-writer Glenn Ficarra played the crazy evil cat known simply as [[NoNameGiven "The Russian"]]. Incidentally, this also leads to a case of...
* FakeNationality:
** Glenn Ficarra is an American, and he provides the voice of the evil [[FakeRussian Russian-accented]] cat who breaks into the Brody home.
** Texas-born actor Charles Howerton plays an uncredited role as a German Shepherd at the Dog World HQ, who, [[RuleOfFunny appropiately enough]], has a German accent.
** Veteran voice actors Creator/BillyWest and Danny Mann, both of them American, voice some of Mr. Tinkles' ninja cats, who are, [[RunningGag once]] [[RuleOfFunny again]], Asian breeds with appropriate accents.
** [[OneSceneWonder Friedrich]], from the second movie, is a German played by an American, [[Series/SaturdayNightLive a Fred Armisen specialty]].
** Also from the sequel, Michael Beattie and [[{{Creator/JeffBennett}} Jeff Bennett]], Canadian and American-born voice actors respectively, provide the voices for the two Scottish tabby mercenaries, Angus and Duncan [=MacDougall=].

* TheOtherDarrin: Lou, Butch and Calico all have new voice actors for the second movie:
** Lou was voiced by Tobey Maguire in the first movie, who was replaced by Creator/NeilPatrickHarris for the next one.
** Butch's voice actor in the first movie was Alec Baldwin, while Nick Nolte plays the part for the sequel.
** Calico was voiced by Jon Lovitz in the original movie and by Wallace Shawn in the second one.
* SavedFromDevelopmentHell: The sequel was intended for release in 2005. After some story rewrites, it was finally released in 2010 instead.
* SequelGap: A 9-year one between the original and ''The Revenge of Kitty Galore''.
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