- Billing Displacement: The posters for the film ran with the bridesmaids theme, depicting all five of them (plus the bride) which was why Chris O'Dowd (Officer Rhodes) doesn't appear, despite playing a more important character than Wendi McLendon-Covey (Rita) or Ellie Kemper (Becca).
- Fake American / Fake Brit: Australians Rose Byrne and Rebel Wilson play an American and a Brit respectively. Averted with Irishman Chris O'Dowd.
- Hey, It's That Guy!: Hey Officer Rhodes, shouldn't you be working down in the basement?
- Name's the Same: The name of Lillian's husband-to-be is Doug(ie), like the groom in the first Hangover movie.
- Reality Subtext: This was Jill Clayburgh's (Annie's mom) last film, as she was secretly fighting leukemia.
- Real-Life Relative: Ben Falcone, who plays Air Marshall Jon, is married to Melissa McCarthy (Megan.)