- Trope Namer: Bonanza is the trope namer for the Cartwright Curse, the tendency for love interests to die or be written out of a series at a high pace for the sake of drama or to maintain the status quo.
- Dan Blocker, who played Hoss, founded the Bonanza Steakhouse restaurant chain. The chain was later bought out by Ponderosa Steakhouse, whose name was also inspired by the TV series.
- The program Bonanza was, at least partially, created due to a deal between RCA and NBC. RCA wanted to sell it's color television sets and NBC made Bonanza as a full color Western, starting with the very first episode in 1959.