Actor Allusion: The short "Sir Yaksalot" has a segment that parodies Godzilla movies and Kaiju films in general, where the Warner siblings attempt to get help against the dragon from a council used to dealing with giant monsters, complete with their voices being (poorly) overdubbed. Perry Mason is among them, referencing Raymond Burr's role in the localized versions of some of the Godzilla movies.
Adored by the Network: The Hub seems to adore this show really much, airing promos for it during every program (even during Animaniacs itself!) and having constant marathons of the show whenever a holiday is near-Christmas, Martin Luther King Day, Super Bowl Sunday, and even President's Day. Not only that, the show airs for three hours on weekdays. They even got Rob Paulsen (Yakko) Jess Harnell (Wakko) and Tress Macneille (Dot) to record new spots, in character, for the show's reruns.
Channel Hop: From FOX Kids to Kids' WB! when it was first-run. In reruns, the show jumped from Cartoon Network to Nickelodeon to Nicktoons TV to The Hub.
Composers: Unlike Tiny Toon Adventures, Animaniacs used a comparatively small but stable group of composers: Richard Stone, Carl Johnson, Steve and Julie Bernstein, Gordon Goodwin, Tim Kelly, and J. Eric Schmidt.
The Danza: Colin, the kid who talks about Randy Beaman, was voiced by Colin Wells.
Edited for Syndication: When Animaniacs aired on Nicktoons Network and Nickelodeon, the opening theme was so plastered with references to the channel that fans rejoiced when the DVDs of the original episodes were released.
Averted with Cartoon Network and The Hub, as both channels air the episodes exactly as they used to air on FOX and the WB.
Enforced Method Acting: Whenever Nathan Ruegger (Skippy) had to laugh as part of the script but couldn't laugh convincingly enough, his dad would come into the studio to tickle him.
Fake Brit: Wakko and Pinky both have British accents provided by American voice actors, but other than their accents, there's really nothing to indicate that they are British.
Anyone who is into Broadway musicals will recognize Rita's voice (singing and speaking) as Bernadette Peters.
Nancy Cartwright (best known as the Simpsons voice actress for Bart, Todd Flanders, Ralph Wiggum, Kearney Zzyzwicznote one of the three bullies — he's the one who looks like a teenaged version of that bald mental patient who thought he was Michael Jackson and only looks like he could be 16 to 18 years old, as a lot of episodes have jokes about Kearney being an adult who looks like a kid, and Nelson Muntz note The other bully character. He's sometimes seen with Dolph, Jimbo, and Kearney, but mostly does bullying at Springfield Elementary, not commit petty crimes around the neighborhood) is Mindy, in one of the few times she's voiced a girl (the other rare time is when she voices Maggie Simpson [when Maggie isn't being voiced by a celebrity like Elizabeth Taylor, Jodie Foster, or James Earl Jones])
The "Good Idea, Bad Idea" and "Mime Time" segments are narrated by Tom Bodett, who is probably best known for his radio ads for Motel 6 ("We'll leave the light on for you").
In "Guardin' the Garden" and "Noah's Lark", the narrator was Ernie Anderson, the "Voice of ABC". They even got him to say "TheLooooooooooooooveArk" in "Noah's Lark"! note The fact that Tom Ruegger and crew indirectly worked for ABC in the past probably has something to do with it, too, but that's neither here or there
Julie Brown (who also played Julie Bruin on Tiny Toon Adventures, was a VJ during the days of MTV when it was a music video channel with the occasional non-music video show, like Beavis And Butthead, House of Style, and The Real World, and had a short-lived show on Comedy Central called Strip Mall where she played a washed-up child actress trying to get her life back together) was Minerva Mink.
Screwed by the Network: Jamie Kellner (whom you may know as the guy who claimed watching television while skipping ads with a DVR is tantamount to stealing, as well as the guy responsible for cancelling all programming from WCW, leading to the company's bankruptcy in 2001) apparently ignored the very high ratings from older audiences while the show was on WB and found the low ratings from kids to be an excuse to cancel the show, though it shouldn't be a surprise as a lot of cartoons created by Warner Brothers at the time were canceled for similar reasons, like Freakazoid! and Road Rovers.
The concept for the show was originally going to star a family/group of green ducks, since the baby version of Plucky Duck from Tiny Toon Adventures went over so well, but wouldn't be related to Plucky and would have nothing to do with the rest of that cast. The team eventually decided that ducks "have been done" and retooled the premise to star 1930s-style cartoon characters.
Pip was originally supposed to be a dog.
Charlie Adler auditioned to do voicework on this show (and his rejection is why he quit Tiny Toon Adventures). One wonders what character he would have voiced if he was hired on the show.