- Alvin and the Chipmunks has Simon for The Chipmunks and Jeanette for The Chipettes.
- Anais and Bobert from The Amazing World of Gumball.
- Sokka from Avatar: The Last Airbender doubles as a Badass Bookworm as he accumulates Character Development. He also averts the 'no romance' part of the trope - he has at least two love interests and Ty Lee says she thinks he's cute at least once.
- The Legend of Korra has Mako (who doubles as The Lancer) as the street-smart and strategic one, and Asami as a Gadgeteer Genius who can fix, drive or fly seemingly anything.
- As in the comics, The Avengers: Earth's Mightiest Heroes! has Iron Man and Ant-Man, who are geniuses in different fields. Bruce Banner would also count, though he's not around as often as his alter-ego.
- Flap Platypus in season 1 of Blinky Bill, in season 2 Shifty Dingo takes over the role and Flap becomes The Lancer. In season 3, Ling Ling the panda qualifies.
- Nonny from Bubble Guppies is smaller than the rest of the characters and wears goggles, and is notably shy and withdrawn for a character on a preschooler's show.
- Captain Simian and the Space Monkeys has a unique example: Dr. Splitz/Splitzy suffers from a Split Personality disorder, and both of them are very intelligent and innovative in their own right. Dr. Splitz is a textbook example — he is the ship's engineer and sometime medic, and has the true heart of a scientist. Splitzy is a Genius Ditz who is extremely skilled in mechanics and acts as translator for Dr.Splitz's Sesquipedalian Loquaciousness. Working together in combat, they make a Badass Bookworm.
- As her name suggests, Gadget Hackwrench from Chip 'n Dale Rescue Rangers.
- Dotty, Pepper's cute little sister on Clue Club. She's a computer whiz (for 1976) and has science and forensic moxie. At age 13.
- Code Lyoko has Jèrèmie Belpois, the only one who knows how to properly use the Supercomputer and the team's Non-Action Guy. He is also The Leader.
- Numbuh Two in Codename: Kids Next Door varies between Small Name, Big Ego, Ace Pilot and Crouching Moron, Hidden Badass. He's generally the most technically skilled of the team though.
- Fishlegs Ingerman in Dragons: Riders of Berk is the resident expert in dragons, the viking equivalent of a zoologyst and seems to have memorize the Great Big Book of Everything about dragons.
- Edd ("Double D") from Ed, Edd n Eddy is highly intelligent, he loves to use "big words", and the other characters will often see him as an Insufferable Genius. But he also shows a lot of common sense, even if he can't understand that other people maybe aren't as interested in reading books and getting knowledge as he is.
- Teebo from Ewoks is this throughout the first season, though he has moments in the second season as well. He listens to the trees, talks to animals, provides solutions to problems the gang is having and forms a closer bond with Logray, the village shaman.
- Ingrid from Fillmore! is the smartest girl in school which is helped by her having a Photographic Memory. She has some nerdy aspects, like owning an Abe Lincoln lunchbox, but it's not played up much.
- In Futurama super-tech is so common that the Smart Guy is actually the only character capable of running the Planet Express delivery company, in the form of Hermes Conrad, a Level 34 beauraucrat and the team's Only Sane Man. Professor Farnsworth also counts, though more in a Genius Ditz / Reluctant Mad Scientist sort of way.
- Dipper Pines in Gravity Falls, along with a Badass Bookworm. Ford is this as well.
- Kin Kujira of Grojband.
- Jimmy Neutron in The Adventures of Jimmy Neutron: Boy Genius. 'Nuff said!
- Heloise on Jimmy Two-Shoes, when she decides to help Jimmy out.
- Valerie on Josie and the Pussycats. Beauty and brains.
- Batman in Justice League is, as in the comics, a mix of this and The Lancer. J'onnJ'onzz is a purer example.
- Mr. Cat from Kaeloo is the only actual smart character on the show, the other "smart" characters being Ditzy Geniuses. He's a pretty good inventor and a Mad Scientist, and he constantly comes up with schemes to trick other people. He averts the "weak" part though as he's actually a very good athlete.
- Wade Load of Kim Possible, a ten-year-old super genius who invents all of Kim's gadgets. Oh, and, he's voiced by Taj Mowry, who also played the titular character of a TV show of the Trope Name.
- L in Men in Black is the team's scientist, medic and forensic investigator all in one.
- Pickles the Drummer, of Metalocalypse, although compared to his bandmates that isn't saying much. Although all of the bandmates have at least one area of expertise despite being catastrophically stupid otherwise, Pickles is implied to be very intelligent: he can play several instruments (and started a highly successful glam rock band as a teenager), understand complex mathematics well enough to explain them to Nathan, read and write music, and seems to have graduated college despite champion-level alcoholism. He might even be a genius, except that because of his implied-to-be-supernatural tolerance, he takes drugs the way other people eat potato chips, and his miserable childhood left him with a level of emotional immaturity that generally puts him on par with the rest of Dethklok.
- Twilight Sparkle takes the role in My Little Pony: Friendship Is Magic, though it's subverted more often than not due to her lack of real world experience to back up her vast book learning. She's certainly capable of some Awesomeness by Analysis however, along with some hardcore exposition.
- Her Evil Counterpart, Sunset Shimmer, is only implied to also be one in My Little Pony: Equestria Girls, with her being Twilight's predecessor as Princess Celestia's student and her rubbing that fact in Twilight's face. Post redemption movies, shorts and books show that she indeed is one, but she's far more of a hands-on learner compared to the generally more bookish and theoretical Twilight.
- Gretchen Grundler of the Recess gang.
- Sam Dullard of Rocket Power is a huge computer whiz and uses that knowledge to help the others improve their sports skills every once in a while. He has also skipped a grade.
- Velma Dinkley in Scooby-Doo.
- Kelly Hamdon in SheZow, as she knows everything related to SheZow.
- Sliced Ice from Skysurfer Strike Force.
- Kyle from South Park often gets this role when compared with the others boys, and even Matt and Trey have called him the group's "smart kid".
- Tako, the unofficial leader of the Sushi Pack, is the one usually called on to think of a plan to defeat the bad guys, and even has a standard "thinking routine". He also offers explanations of more complicated terms that come up in the show.
- In Teenage Mutant Ninja Turtles (2003), Donatello's intelligence rises sharply to the point where he can build just about anything within a day or two (it seems to vary on how soon the team needs it), and figures out how to adapt Utrom tech, along with almost all other alien technology. He's also the guy with the Simple Staff, and generally considered the Technical Pacifist.
- Teen Titans:
- Cyborg, a Genius Bruiser, fills this seat of the Five-Man Band.
- Raven has elements of this, too, despite primarily being The Lancer. Of course, Cyborg also sometimes fills the role of The Lancer despite primarily being The Smart Guy, so it all evens out.
- Robin, being The Strategist and Batman's apprentice, can fill this role as well, especially when assessing new threats or being Mr. Exposition.
- Shy-but-sensible Austin of The Backyardigans, both in and out of character. Uniqua also tends to play scientific types, while more excitable Pablo is usually used to play with the concept.
- Buckwheat on The Little Rascals is a Gadgeteer Genius, in one of several departures from the Our Gang theatrical shorts.
- Tanya of The Mighty Ducks is the resident Gadgeteer Genius and overall tech expert, although she's no weakling on the battlefield or the hockey rink. She tends to stutter and lisp a bit, since her brain is moving faster than she can speak.
- In The Penguins of Madagascar, Kowalski is both The Lancer to Skipper, and the smart guy. While not short, he is notably the slimmest of all the penguins, and their Technical Pacifist. He's notably the Mad Scientist and Gadgeteer Genius types.
- Blossom and Professor Utonium on The Powerpuff Girls both show some moxie in the intelligence department, but they will often get Flanderized (Blossom as egocentric, the Professor as a haplessly overconcerned parent) to keep them from being too one-dimensional.
- Egon Spengler in The Real Ghostbusters: All the characters are very intelligent, after all, they are all scientists,note but Egon is so intelligent that he makes the other characters look dumb in comparison. In the Sequel Series Extreme Ghostbusters the role lands in Roland.
- Lisa Simpson in The Simpsons. Marge as well, in a few cases, but she is just a bit too oblivious to what constitutes as normal human behavior to do any discrediting.
- Sally, Uncle Chuck and Rotor take up this role in Sonic Sat Am, mostly Sally though. Sal also qualifies as The Leader.
- Wildcat in TaleSpin is an exceptionally good mechanic and plane engineer, albeit a little crazy. Some could say that Rebecca is also the “Smart Girl” of the show as she’s the more grounded, but at the same time some of her Get Rich Quick Scheme do not work.
- In The Tick, the comics, animated and live-action series, the Tick's moth-garbed sidekick, Arthur, fills the role of the Smart Guy.
- In Transformers: Beast Wars, Dinobot The Lancer was a Proud Warrior Race Guy with little respect for trickery. Rhinox The Big Guy was a Genius Bruiser who dealt with equipment as a Mr. Fixit. Rattrap The Smart Guy was second-in-command and more skilled in the realm of infiltration, sabotage and underhanded tactics. In fact, you could break the three of them down into a triangle of hybrids: Dinobot = Lancer/Big Guy; Rhinox = Big Guy/Smart Guy; Rattrap = Smart Guy/Lancer.
- Ratchet in both Transformers Animated and Transformers Prime.
- In Transformers Generation One, Wheeljack and Ratchet shared this role in the first season, Perceptor joined in as a third Smart Guy in the second season, and the third season saw Perceptor become the sole Smart Guy after Wheeljack and Ratchet's deaths in The Movie. The fourth "season" (really just a few episodes) introduced Brainstorm for this role, but the show ended before much could be done with him.
- Mo' Money from Waynehead fills this role on the show.
- Winx Club made a half-hearted attempt to avert the "usually the technologically-minded character" aspect by having the girls mention that Musa and Flora get the best grades; nevertheless, the show kept using Tecna in the role of The Smart Girl. Timmy is also one for the Specialists, being the tech expert for them.
- In the 4Kids version this turns a little racist; Flora's name is cut out of the best grades line, meaning that Musa, the Asian-inspired character, is the only one mentioned.
- Walden from Wow! Wow! Wubbzy! fills this role on the show. As the theme song says, "he knows about science and books and art."