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Tear Jerker: Yo-Jin-Bo
The Bad endings of Yo-Jin-Bo are all pretty much tear jerkers, but special mention goes to Ittosai's Bad ending for his anguished cry of "The people I love always run away from me!" when the pendant forces Sayori back to her own time literally in the middle of Ittosai's attempt to confess his feelings to her. Owww.