This is based on opinion. Please don't list it on a work's trope example list.
Tear Jerker / William Joyce
Mary Katherine Joyce, Bill's daughter and the girl who gave him the inspiration for The Guardians of Childhood series. She died of a brain tumor at the age of 18. RIP, Mary Katherine. You left us and countless millions with a wonderful gift to the world.
The main character in Epic (which Bill also produced) was named after his poor late daughter..
In January 2016, Bill's wife Frances Elizabeth Baucum Joyce, died after a long battle with amyotrophic lateral sclerosis at age 55.