* [[spoiler: C. D. Parker's death.]]
** Even worse, [[spoiler: Walker and Trivette grimly having to exhume his grave to see if he was poisoned on a rainy day, leading to a montage of all the good times they had with their old friend.]]
-->'''Walker:''' Tears from Heaven.
* The ending of "Lucas" two-parter, [[spoiler: in the first part Lucas mother dies]] and in the second part [[spoiler: Lucas dies from AIDS]]. Two-parter is practically a TearJerker episode.
* An episode featuring a brother-and-sister pair of Irish freedom fighters, out to avenge the death of their parents by killing those responsible. When Walker and company finally catch up with them in a high rise building where they've barricaded themselves, the young woman looks at her brother and gently says, "Let's go home". He nods in agreement, and they leap to their deaths. It's a surprisingly poignant moment when you realize these were just two very angry and misguided young people who let their feelings of vengeance get out of control. A rare example of a SympatheticMurderer on this show.
* The episode where a child is bullied because of his poverty-stricken life and ends up standing on his school rooftop, poised to commit suicide. Walker begs him not to do it, but the poor kid takes the plunge anyway.
* The ending of "An Innocent Man." A repairman was framed for the horrific murders of several women, and the real killer visited him in prison, blackmailing him into confessing, threatening to kill his family if he didn't. The man is so terrified for his wife and children's safety he endures a guilty plea ''and'' getting the death penalty. He even refuses to confide in Walker. But at the end, when the real killer is caught, Walker and Trivette rush and stop the impending execution. The repairman has to be doubly reassured the real killer is in custody, before he breaks into into pathetically grateful sobs.
* Pretty much all of "Stolen Lullaby," but especially the scene where the baby is returned to her mother.