When Beth begins to manifest her own guilt at realizing she entered the sphere, too. The music becomes dissonantly serene and wistful. She manifests Norman screaming at her, "You almost got me KILLED!" while Harry taunts on a monitor, "Calling Dr. Beth Halpern - come back to reality!" Worse, the corpse of Fox washes against her and murmurs, "Beth." No wonder she's reduced to a quivering, apologetic mess when Norman finds her.
Norman mildly despairing that they were given an incredible gift that he desperately wanted to keep, with his admission that he and humankind just weren't ready for the gift.