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Tear Jerker: Oliver!
"Where is Love?", "As Long As He Needs Me", the reprise of "As Long...", and the reprise of "Reviewing the Situation" (it's different in the movie).
Her death, and her situation, really. A child pickpocket who was unable to get out and stuck with an abusive boyfriend. She tries to save Oliver from what she knows will happen and is beaten to death!!
Making it worse is the fact that Nancy was only in a position to be killed by him because she turned down Mr. Brownlow's offer to go to the police. Even with her Heel-Face Turn, she still loved Sikes enough to keep him out of prison. And the bastard ends up killing her because of it.
Also the fact that she gave Oliver one last hug before she dies is gut wrenching.