Pepper's "I'm Sorry" song from Penny for Your Laughs. The whole song shows Pepper trying to cheer up Penny Ling only to fail miserably. She offers Penny a balloon, and it gets popped by a bird. She offers her an ice cream cone, it falls on her head. She tries to play catch with her with different balls, and each time Penny gets hit by the ball. Finally, Pepper gives Penny a flower, and when Penny sniffs it, a bee comes out of it and stings her on the nose. And to make this even more of a tearjerker, Penny cries at the end and her tears form a broken heart on the ground.
Vinnie going into a Heroic BSOD after being harshly rejected by the judges in "So You Skink You Can Dance."
Zoe's reaction to Blythe altering the birthday dress that was made for her in "Terriers and Tiaras."
The season one finale in general. Blythe leaving to fashion camp for the summer. Think about that.....
In "Commercial Success" when Mrs Twombly who was very excited to be in the commercial was cut out entirely Kathleen Barr does such an authentic cry, that you can't help but feel sorry for Mrs. Twombly.
Pepper in "Sweet Pepper", she spends most of the episode upset because she can't bring herself to talk to Captain Cuddles without punching him. She's so stressed about it that she actually snaps at Buttercream at one point.
Russell on the verge of tears in The Hedgehog In The Plastic Bubble due to his quilling problem
In "Sunil's Sick Day" when Sunil and Vinnie imagine what life would be like without the other when they start to miss each other.
In "Stand Up Stinker" all Pepper wants is for humans to appreciate her jokes. Despite her wish came true (her jokes appearing on a nightly talk show) she still will never get the credit.
Not so much Tear Jerker, but you do feel really bad for Penny in "Secret Cupet" when she gets more and more upset with Russell's flirting. She sounds like she's about to cry when she runs from him saying she needs a vacation.
In "Hamster Hoods" we see two stray kittens drinking dirty water in an ally. The two guest pet hamsters were able to cheer them up with toys but it's still really sad.
The ferret's problem in "Tongue Tied" was pretty sad Imagine, you're separated from your owner, lost in a giant city, knowing nobody, no-one there to help you, except one human. Except said human doesn't understand what you're trying to tell her, and you only have a few hours or you and your owner will be separated forever]
Penny Ling's dilemma in "What's So Scary About the Jungle? Everything!" She gets the chance to meet the host of her favorite show, only to discover that she's deathly afraid of her. Penny Ling becomes so depressed because of this, that she doesn't even laugh when Minka tickles her. Poor Penny.