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Tear Jerker: Kurtjmac
At the beginning of Far Lands or Bust Episode #178, there's a noticeable emptiness when there is no *WOOF* to begin the episode, which had been tradition for quite some time before Wolfie disappeared during the F Lo B-athon Livestream.
When Wolfie disappears in the 2012 F Lo B-aton, Bdubs makes a comparison to Jurassic Bark. Within 30 seconds, there isn't a dry eye in the house.