- The ending of Half-Life 2 Episode 2, where Eli Vance is killed by a Combine Advisor. Made particularly tragic in that his last words is to tell his daughter to look away. Alyx's heartbroken sobbing, begging her dad not to leave her as the screen goes dark and the credits begin crawling doesn't help matters either.
- The fate of the rebels Sandy and Lazlo. If you manage to save Sandy, then he tells you to go on ahead, and that there's "something [he] has to do". The Tear Jerker is the fact that it sounds awfully like he's going to follow after his friend; it's entirely likely he was just going to bury Lazlo's body, though.
- The uncertain fate of Shepherd. Somewhere, he's still stuck in Limbo.
- The Nihilanth is the last of his kind, after his entire species has been murdered by the Combine. Imagine how alone he must feel after losing anyone he (potentially) cared about. Killing him and thus rendering his species extinct is a depressing thought.
- Fan content, but still sad and beautiful. Compounded by one of the video's comments:
A requiem.For Winston, Lazlo, Eli Vance, and the rebel casualties in the war against the Combine.For the billions of people killed by the Universal Union. For the civilization that took 10,000 years to build...and took 7 hours to be annihilated.A requiem for humanity. A salute to the fallen. May the war go on, until humanity is free...or extinct.
- The crowbar gets incinerated at the beginning of the last chapter of Half-Life 2. It's a tragic way to lose a trusty companion.
- This fan made video is particularly poignant and sad.
- On August 25th, 2017, the 21st anniversary of Valve, Marc Laidlaw shared the whole story of Half-Life 2's third episode on his official site, initially disguised as Fan Fiction with genderswapped characters and different names, but mirrored on other sites with edits that restored the Half-Life characters and names. It is incredibly sad to read, as it all but officially confirmed that Half-Life is done.
"It has been a circuitous path to lands I once knew, and surprising to see how much the terrain has changed. Enough time has passed that few remember me, or what I was saying when last I spoke, or what precisely we hoped to accomplish. At this point, the resistance will have failed or succeeded, no thanks to me. Old friends have been silenced, or fallen by the wayside. I no longer know or recognize most members of the research team, though I believe the spirit of rebellion still persists. I expect you know better than I the appropriate course of action, and I leave you to it. Expect no further correspondence from me regarding these matters; this is my final episode."
- The final part implies that Gordon ends up on Earth so far into the future that few even remember his name or his deeds, and is uncertain if the resistance even won the war...or it could be a reflection on the current state of Valve, and how Half-Life has been forgotten by the very studio who had created it. In any case, it is depressing.
"Yours in infinite finality,Gordon Freeman, Ph.D"
- The fact that this is both the first time that we hear Gordon speak and the last.
- Marc Laidlaw posted the story on the 21st anniversary of Valve. The series that proved to be Valve's Breakthrough Hit and influences first-person shooters to this day, that fans waited a decade for the resolution of after the Cliffhanger ending of Episode 2, ends on a blog post from its retired writer.
- The worst part about the blog post is that Valve absolutely doesn't seem to care. Fans have long waited for a continuation and a conclusion to the Half-Life series or to even get Episode 3/Half-Life 3 only for Valve to downright refuse to comment on it (and just their games in general). It made a majority of those who were waiting for so long feel they've waited for nothing and have turned their backs on Valve (and by some extent Gabe Newell who also refuses to comment about Episode 3) and consider them a Fallen Hero.
- The fandom has started making many videos that re-create what Laidlaw put out in his blog post using SFM, many showcasing what the ending could've been. This one is so incredibly epic and accurate, that you can only wonder what it would've been like to see this happen in the game.