Final Fantasy IV has plenty of moments, especially when Porom and Palom, two child-wizards, turned themselves to stone to save their allies from being crushed by the walls of a collapsing room. Even though we get some good news about them during a later boss fight, that moment is still a heartbreaker. Made even worse when you remember they're only five years old.
Also there is the scene where Edge's parents kill themselves in front of Edge as he is begging them not to.
The sacrifices of Yang and Cid, within about two minutes of each other and the party pleading for both of them not to go through with it.
Starting with Yang, who sought to stop the Tower of Babil's cannon from destroying the dwarves by using his own body to make it misfire. This makes the introduction to Edge, his inevitable fifth-slot replacement, sting a lot more.
Yang: Forgive me... (Yang kicks the group out of the room and closes the door in front of them) Cecil: Yang!? Yang!! Yang: If you should see my wife again, tell her to live enough for us both. Kain: Don't be a fool! Open the door! Rydia: Yang! Rosa: Please, Yang, don't throw your life away! Yang: It's been an honor fighting with you. Cecil: Open the door, Yang! (commence final firing sequence) Yang: Gaaaaaaaaaaaaah!! *boom* Cecil: Yang!
And then there's Cid, who jumped off the Enterprise with the FFIV equivalent of a tactical nuke with the intent of shutting the underground behind them and stop the Red Wings' pursuit. And just when you thought you had him back.
Rydia: They're closing on us! Cid: Come on... Enterprise! (cue a small explosion and smoke pouring from one of the engines) Cid: The engines can't take this! Cecil, take over! Rosa: Cid! Rydia: What are you doing?! (Cid runs to the siderail and pulls out the bomb) Cid: Once you breach the surface, I'll seal off the hole with this! Rosa: No, not you too! Cid: I was hoping I'd get to see your kids someday, but someone's got to keep Yang company. You get yourselves back to Baron, talk to my boys when you get there. Rosa: But Cid! Rydia: You'll die! Cid: And so young, too! (jumps of airship carrying hand-nuke) Bombs away! Try stopping this, Golbez! My once-in-a-lifetime unaided flight! *kaboom* (cue shift of scene to the Enterprise overlooking the sealed mountain behind Agart village) Rydia: Cid... Rosa: (leans into Cecil) One after another... Kain: Rushing to die like fools! (pounds fist into railing) Cecil: We go to Baron — for Cid.
In the Advance version, Kain gives us this line:
Kain: Everyone chooses death too quickly...
When Theodor AKA Golbez tries to use Cure on his dead father.
Just before this scene, Klu Ya is seen chastising his son for not being diligent with his magic studies, not even mastering a basic spell like Cure. So on top of failing to revive his father, Theodor was also burdened with the fact that if he'd just listened to his father, he could have saved him.
Tellah's death, made even more poignant when you beat the game and realize out of all of the Disney Deaths, he's one of the only characters who actually stays dead through the end.
In the Final Boss fight, when Tellah shows up, you realize that it's probably his soul from the afterlife.
Tellah's very backstory; he wants revenge on Golbez for killing Anna and is seeking a Dangerous Forbidden Technique to do it, aware that trying to cast Meteor will drain his life force because at his age he's too weak to survive the strain. And he doesn't care. As far as the game implies, Tellah has no other family anymore, which is likely why he was so against Anna eloping with Edward, he didn't want to lose his only family. And now that she's gone, he feels he has nothing to live for anymore so he might as well spend his life performing a Heroic Sacrifice to get vengeance for her.
When Golbez is reverted back to his senses, it is very sad to see Cecil's realization that he was fighting his own brother.
The fact that two brothers are forced to be enemies by no fault of their own is very sad itself. Golbez, really, was just as much a victim as everyone else because he was used by Zemus and is in fact a good person, and the fact is everyone has good and bad inside them.
Almost every scene mentioned on this page usually play the theme Cry In Sorrow. A very fitting name indeed.