Tear Jerker: Fahrenheit
- The opening where Lucas is a zombie, and sitting alone being depressed. The whole game explains of how did he end up in that state.
- The death of Tiffany Harper.
- The death of Jade.
- The death of any of the children in the Wishita flashback. Made even worse because, unlike the above two, it is avoidable.
- The 'bad' ending, in which most of humanity has frozen to death and the survivors live in sewers praying for a savior/