This is based on opinion. Please don't list it on a work's trope example list.
Tear Jerker / Children Of Eden
The expulsion, Abel's death, and the flood, natch.
Eve's monologue and the title song, "Children of Eden" at the end of Act I. Father finally speaks to her for the first time after The Fall. She sings a goodbye song to her large family, and her death is presented as walking up the staircase into Father's arms.
"The Hardest Part of Love"
Noah: That the hardest part of love,
Father: and the rarest part of love
Both: And the truest part of love...is letting go.
The reprise of the big love song then becomes about the entire family staying together:
In whatever time we have, for as long as we are living
We can face whatever comes, if we face it now as one
If there's silence in the sky, in a world without a future
We will swear to be together in whatever time we have.
The finale, In the Beginning
That little reprise of 'Children of Eden' at the end of "In The Beginning" is almost too beautiful for me to actually listen to.
My choir sang this at my best friend's graduation (it was our fall show that year). It was particularly moving, with the parts of Japeth and Yonah sung by two graduating seniors ('This step is once again our fist/We set our feet upon a virgin land...") and the freshman chorus joining in at the last minute:
We cannot know what will occur
Just make our journey worth the taking...
"Stranger To The Rain" is heartbreaking.
I will dance before the lightning to music sacred and profane
Shed no tears for me, light no candle for my sake
The journey I am making now is one we all must make...